Approximate dose equivalencies based on clinical references. Individual response varies.
| Medication | Typical Starting | Usual Range | Approx. Fluoxetine Equivalent |
|---|---|---|---|
| Fluoxetine | 20 mg | 20–60 mg | 20 mg = 20 mg |
| Sertraline | 50 mg | 50–200 mg | 50 mg ≈ 20 mg |
| Escitalopram | 10 mg | 10–20 mg | 10 mg ≈ 20 mg |
| Citalopram | 20 mg | 20–40 mg | 20 mg ≈ 20 mg |
| Paroxetine | 20 mg | 20–50 mg | 20 mg ≈ 20 mg |
| Venlafaxine XR | 75 mg | 75–225 mg | 75 mg ≈ 20 mg |
| Duloxetine | 30–60 mg | 60 mg | 60 mg ≈ 20–30 mg |
| Bupropion XL | 150 mg | 150–300 mg | 150–300 mg ≈ 20–40 mg |
| Mirtazapine | 15 mg | 15–45 mg | 30 mg ≈ 20–30 mg |
Equivalencies are approximate and based on clinical practice and published dose-equivalence studies (e.g., Hayasaka et al.). Not a substitute for clinical judgment. Consider half-life, CYP interactions, and patient-specific factors when switching.